CANCER BIOLOGY AND EMERGING THERAPEUTICS: FROM GENES TO TARGETED THERAPIES

Authors

Eligros kujur (ed)
shri shankaracharya professional university bhilai (C.G.) Pin
Dr. Gunmeek Kaur (ed)
Assistant Professor , Luxmi Bai Dental College and Hospital in Patiala, Punjab
Dr. Sumit Bhatt (ed)
Professor and PhD Scholar, Department of oral and maxillofacial surgery at Rajasthan Dental College and hospital under Nirwan University Jaipur
Ms. Kuppili Praveena (ed)
Assistant professor, C.M.Dubey PG College Bilaspur (C.G) Pin: 495004

Keywords:

• Cancer biology • Oncogenes • Tumor suppressor genes • Epigenetics • Targeted therapy • Immunotherapy • Gene therapy • Molecular glues • Precision medicine • Multi-omics • Tumor microenvironment • Signal transduction pathways • CRISPR/Cas9 • Checkpoint inhibitors

Synopsis

Cancer is a complex and multifactorial disease driven by genetic mutations, epigenetic alterations, and dysregulated cellular pathways. Advances in molecular biology have unraveled the intricate mechanisms underlying tumor initiation, progression, and metastasis, highlighting the roles of oncogenes, tumor suppressor genes, and the tumor microenvironment. These insights have paved the way for the development of emerging therapeutics that move beyond conventional chemotherapy. Targeted therapies, immunotherapies, gene editing technologies, and molecular glues represent a new era of precision medicine, offering improved efficacy and reduced toxicity. This review explores the genetic foundations of cancer and the evolution of therapeutic strategies, emphasizing the integration of multi-omics and personalized approaches to revolutionize cancer treatment.

Chapters

Chapter-1: FUNDAMENTALS OF CANCER BIOLOGY
Dr. MADHUSMITA SAHU, Dr. GAURAV BHATNAGAR (PT), Dr. RISHA KAMBLE (PT), Dr. JAYASANKAR NARAYANAN, Dr. T. TAMILANBAN
View Chapter
Chapter-2: GENETIC AND EPIGENETIC MECHANISMS OF CARCINOGENESIS
Dr. AVINASH JORIYA, Dr. FORAM PATEL, Dr. KAJAL RAJESHBHAI PATEL, Dr. PARESHKUMAR N. PATEL, MONU KUMAR (MK GROVER)
View Chapter
Chapter-3: TUMOR MICROENVIRONMENT AND ANGIOGENESIS
Ms. PRAJAKTA SHINDE, Dr. SHUBHANGI PAREEK, Dr. SHREEYAM MOHAPATRA, POONAM SUBHASH SABLE, DR. RESHU TIWARI
View Chapter
Chapter-4: SIGNAL TRANSDUCTION PATHWAYS IN CANCER PROGRESSION
Dr. DEEPESH LALL, DR. RESHU TIWARI, V. GEETHA, Mr. PHANSE MILIND DILIP, Ms. SNNEHAA BHOSLE
View Chapter
Chapter- 5:MOLECULAR DIAGNOSIS AND BIOMARKERS IN ONCOLOGY
Dr. ROHIT NARENDRA RATHOD, Dr. GUNMEEK KAUR, Dr.ALFRED JOEL WYLIE, Dr. REVANT CHOLE, Dr. YAKSHI SINGH
View Chapter
Chapter-6:CHEMOTHERAPY AND RADIOTHERAPY: MECHANISMS AND LIMITATIONS
Dr. T.DEBORAH PARIPURANAM, Dr. PRACHI HAZARI, DR. RASHMI M, DR. SONIA KUKRETI
View Chapter
Chapter-7:TARGETED THERAPY AND MONOCLONAL ANTIBODIES
PROF. (Dr.) SANTANU CHAKRABORTY, Dr. MANAMI DHIBAR, Mr. BISHAL SARKAR, Mr. PRASIT ROY, BITHIKA BANERJEE
View Chapter
Chapter-8: IMMUNOTHERAPY AND IMMUNE CHECKPOINT INHIBITORS
Dr. SHRADDHA WALEKAR GHAISAS, Dr. HIREN HANSRAJ PATADIYA, RASHMI, SANDHYA, NIKITA SAHU
View Chapter
Chapter-9: NANOTECHNOLOGY AND NOVEL DRUG DELIVERY SYSTEMS IN CANCER
Dr. JAGANMAI G, Dr. DEEPAK PRASHAR, Mrs. POONAM, Ms. SHIVANGI VERMA, Dr. AVINASH JORIYA
View Chapter
Chapter-10: PERSONALIZED AND PRECISION ONCOLOGY: THE FUTURE OF CANCER TREATMENT
AERA PALAVIYA, YASH PAL, JAINESH PATEL, RAHUL DESAI, Ms. BHUMIKA PANCHAL
View Chapter
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Published

September 26, 2025
Copyright (c) 2025 Nexus Knowledge Publication (Imprint of AKT Multitask Consultancy)

License

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Details about this monograph

ISBN-10 (02)

978-81-985724-0-0

ISBN-13 (15)

978-81-985724-0-0

How to Cite

kujur, E. ., Kaur, D. G. ., Bhatt, D. S. ., & Praveena , M. K. . (Eds.). (2025). CANCER BIOLOGY AND EMERGING THERAPEUTICS: FROM GENES TO TARGETED THERAPIES. Nexus Knowledge Publication (Imprint of AKT Multitask Consultancy). https://nknpub.com/1/catalog/book/14