CENTRAL NERVOUS SYSTEM PHARMACOLOGY

Authors

DR. SAURABH SHRIVASTAVA, Associate Professor Shri Shankaracharya College of Pharmaceutical Sciences, Bhilai, 490020; DR. SUMAN SHRIVASTAVA, Assistant Professor Shri Shankaracharya College of Pharmaceutical Sciences, Bhilai, 490020; DR. DHAVAL PATEL, Assistant General Manager - Product Development Jamp India Pharmaceutical Pvt Ltd, Ahmedabad; DR. SAKSHAR SAHA, Assistant Professor, Department of Pharmaceutical Technology, JIS University, Agarpara, Kolkata Pin -700109; MR. KRISHNENDU RAY, Principal Uttaran Institute Of Medical Sciences, Khana Junction, Purba Burdwan, West Bengal, 713141

Synopsis

 

Central Nervous System Pharmacology explores the mechanisms by which drugs influence brain and spinal cord function. It focuses on agents that either stimulate or depress neural activity, targeting neurotransmitter systems to treat neurological and psychiatric disorders. These drugs act on specific receptors—such as ionotropic and metabotropic types—modulating synaptic transmission and neuronal excitability.

Key neurotransmitters involved include dopamine, serotonin, GABA, glutamate, acetylcholine, and norepinephrine, each playing distinct roles in cognition, mood, motor control, and autonomic regulation. CNS-active drugs are classified into categories such as anxiolytics, antidepressants, antipsychotics, anticonvulsants, sedatives, stimulants, and neuroprotective agents.

Understanding CNS pharmacology is essential for developing therapies for conditions like depression, anxiety, epilepsy, Parkinson’s disease, schizophrenia, and Alzheimer’s disease. Advances in genomics and neuropharmacology are paving the way for personalized medicine and more targeted drug development strategies.

 

pharmacology

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Volume

ADVANCED PHARMACOLOGY – I

Pages

94-141

Published

July 16, 2025
Copyright (c) 2025 Dr. Avinash Joriya (Volume editor); DR. DHAVAL PATEL, DR. SAKSHAR SAHA, MR. KRISHNENDU RAY, DR. ANURAG RAWAT, DR. SANJEEV KUMAR, DR. RAKESH SAHEBRAO JADHAV, ANSHUL RAM, V. GEETHA, SUJIT RAMCHANDRA DESHMUKH, MAYURI SHATRUGHNA GHADGE, DR. RAKESH SAHEBRAO JADHAV, ARPIT GAWSHINDE, DR. SUMAN SHRIVASTAVA, DR. SAURABH SHRIVASTAVA, DR. SONIA KUKRETI (Chapter Author); Mrs. Nityashree Mohapatra, Ms. Rama Soni, Dr. Keserla Bhavani (Volume editor); MR. LOKESH KUMAR, SUDHANSHU SHANDILYA, DR. G. VENKATA KARTHIK KUMAR REDDY, SHRAVANI PRAKASH PAWAR, DR. JAYANTI TIWARI, LEKHANA PALLAGANI, SOUMYAJIT PANDA, DR. RAKESH SAHEBRAO JADHAV, DR. MOIDUL ISLAM JUDDER, DR. MUKESH KUMAR MEENA (Chapter Author)

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How to Cite

SHRIVASTAVA, D. S. ., SHRIVASTAVA, D. S. ., PATEL, D. D. ., SAHA, D. S. ., & RAY, M. K. . (2025). CENTRAL NERVOUS SYSTEM PHARMACOLOGY. In D. A. . Joriya, M. N. . Mohapatra, M. R. . Soni, & D. K. . Bhavani (Eds.), ADVANCED PHARMACOLOGY – I (pp. 94-141). Nexus Knowledge Publication (Imprint of AKT Multitask Consultancy). https://nknpub.com/1/catalog/book/10/chapter/33